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BMCBI
2011
12 years 11 months ago
PRIN, a predicted rice interactome network
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
Haibin Gu, Pengcheng Zhu, Yinming Jiao, Yijun Meng...
AAAI
2008
13 years 10 months ago
Generating Application-Specific Benchmark Models for Complex Systems
Automated generators for synthetic models and data can play a crucial role in designing new algorithms/modelframeworks, given the sparsity of benchmark models for empirical analys...
Jun Wang, Gregory M. Provan
BMCBI
2002
214views more  BMCBI 2002»
13 years 7 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2006
136views more  BMCBI 2006»
13 years 7 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
GECCO
2008
Springer
175views Optimization» more  GECCO 2008»
13 years 8 months ago
Using differential evolution for symbolic regression and numerical constant creation
One problem that has plagued Genetic Programming (GP) and its derivatives is numerical constant creation. Given a mathematical formula expressed as a tree structure, the leaf node...
Brian M. Cerny, Peter C. Nelson, Chi Zhou