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BMCBI
2010
112views more  BMCBI 2010»
13 years 8 months ago
Knowledge-based analysis of microarrays for the discovery of transcriptional regulation relationships
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
BMCBI
2010
172views more  BMCBI 2010»
13 years 3 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
GECCO
2004
Springer
138views Optimization» more  GECCO 2004»
14 years 1 months ago
Comparing Genetic Programming and Evolution Strategies on Inferring Gene Regulatory Networks
Abstract. In recent years several strategies for inferring gene regulatory networks from observed time series data of gene expression have been suggested based on Evolutionary Algo...
Felix Streichert, Hannes Planatscher, Christian Sp...
ALMOB
2007
111views more  ALMOB 2007»
13 years 8 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...
BMCBI
2006
239views more  BMCBI 2006»
13 years 8 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...