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ICDM
2003
IEEE
148views Data Mining» more  ICDM 2003»
14 years 4 months ago
Inference of Protein-Protein Interactions by Unlikely Profile Pair
We note that a set of statistically “unusual” proteinprofile pairs in experimentally determined database of protein-protein interactions can typify protein-protein interaction...
Byung-Hoon Park, George Ostrouchov, Gong-Xin Yu, A...
NIPS
2004
14 years 11 days ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
CSB
2002
IEEE
230views Bioinformatics» more  CSB 2002»
14 years 4 months ago
Prediction of Protein Function Using Protein-Protein Interaction Data
Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, ...
BMCBI
2005
126views more  BMCBI 2005»
13 years 11 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...
BMCBI
2008
124views more  BMCBI 2008»
13 years 11 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo