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BMCBI
2007
153views more  BMCBI 2007»
13 years 7 months ago
A new pairwise kernel for biological network inference with support vector machines
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
BMCBI
2005
178views more  BMCBI 2005»
13 years 7 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 7 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
ICML
2009
IEEE
14 years 8 months ago
Dynamic mixed membership blockmodel for evolving networks
In a dynamic social or biological environment, interactions between the underlying actors can undergo large and systematic changes. Each actor can assume multiple roles and their ...
Wenjie Fu, Le Song, Eric P. Xing
BMCBI
2008
202views more  BMCBI 2008»
13 years 7 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...