57 search results - page 7 / 12 » Inferring Regulatory Systems with Noisy Pathway Information |
IDA
2009
Springer
13 years 6 months ago
2009
Springer
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
RECOMB
2003
Springer
14 years 9 months ago
2003
Springer
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
BMCBI
2007
13 years 9 months ago
2007
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
NAR
2008
13 years 7 months ago
2008
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
BMCBI
2007
13 years 9 months ago
2007
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...