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BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Functional characterization and topological modularity of molecular interaction networks
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Jayesh Pandey, Mehmet Koyutürk, Ananth Grama
BMCBI
2008
98views more  BMCBI 2008»
13 years 7 months ago
Empirical Bayes models for multiple probe type microarrays at the probe level
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
Magnus Åstrand, Petter Mostad, Mats Rudemo
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong
BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and e
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...
BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on
Background: A number of studies on biological networks have been carried out to unravel the topological characteristics that can explain the functional importance of network nodes...
Yung-Keun Kwon, Sun Shim Choi, Kwang-Hyun Cho