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» Inferring differentiation pathways from gene expression
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ISMB
2008
14 years 1 months ago
Inferring differentiation pathways from gene expression
Ivan G. Costa, Stefan Roepcke, Christoph Hafemeist...
NAR
2010
123views more  NAR 2010»
13 years 5 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
BMCBI
2005
114views more  BMCBI 2005»
13 years 10 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
ICASSP
2011
IEEE
13 years 2 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero
BMCBI
2008
97views more  BMCBI 2008»
13 years 11 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar