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» Inferring differentiation pathways from gene expression
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BMCBI
2008
132views more  BMCBI 2008»
13 years 11 months ago
Very Important Pool (VIP) genes - an application for microarray-based molecular signatures
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
BMCBI
2008
130views more  BMCBI 2008»
13 years 11 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2008
145views more  BMCBI 2008»
13 years 11 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2010
176views more  BMCBI 2010»
13 years 11 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2010
172views more  BMCBI 2010»
13 years 6 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...