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» Inferring differentiation pathways from gene expression
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2008
IEEE
14 years 4 months ago
Inferring the Function of Genes from Synthetic Lethal Mutations
—Techniques for detecting synthetic lethal mutations in double gene deletion experiments are emerging as powerful tool for analysing genes in parallel or overlapping pathways wit...
Oliver Ray, Christopher H. Bryant
BMCBI
2008
161views more  BMCBI 2008»
13 years 10 months ago
Inferring gene expression dynamics via functional regression analysis
Background: Temporal gene expression profiles characterize the time-dynamics of expression of specific genes and are increasingly collected in current gene expression experiments....
Hans-Georg Müller, Jeng-Min Chiou, Xiaoyan Le...
BMCBI
2002
188views more  BMCBI 2002»
13 years 9 months ago
The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
Background: The biomedical community is developing new methods of data analysis to more efficiently process the massive data sets produced by microarray experiments. Systematic an...
David M. Mutch, Alvin Berger, Robert Mansourian, A...
BMCBI
2006
200views more  BMCBI 2006»
13 years 10 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
BMCBI
2008
126views more  BMCBI 2008»
13 years 10 months ago
GeneChaser: Identifying all biological and clinical conditions in which genes of interest are differentially expressed
Background: The amount of gene expression data in the public repositories, such as NCBI Gene Expression Omnibus (GEO) has grown exponentially, and provides a gold mine for bioinfo...
Rong Chen, Rohan Mallelwar, Ajit Thosar, Shivkumar...