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» Inferring differentiation pathways from gene expression
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BMCBI
2006
133views more  BMCBI 2006»
13 years 7 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
BIOCOMP
2008
13 years 9 months ago
Prediction of Protein Function Using Graph Container and Message Passing
We introduce a novel parameter called container flux, which is used to measure the information sharing capacity between two distinct nodes in a graph. Other useful information, bot...
Hongbo Zhou, Qiang Shawn Cheng, Mehdi Zargham
BMCBI
2010
95views more  BMCBI 2010»
13 years 7 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
NAR
2011
290views Computer Vision» more  NAR 2011»
12 years 10 months ago
AHD2.0: an update version of Arabidopsis Hormone Database for plant systematic studies
Phytohormone studies enlightened our knowledge of plant responses to various changes. To provide a systematic and comprehensive view of genes participating in plant hormonal regul...
Zhiqiang Jiang, Xiao-Chuan Liu, Zhiyu Peng, Yinan ...
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...