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» Inferring gene regression networks with model trees
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BMCBI
2005
88views more  BMCBI 2005»
13 years 8 months ago
Using large-scale perturbations in gene network reconstruction
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computatio...
Thomas MacCarthy, Andrew Pomiankowski, Robert Seym...
BMCBI
2011
13 years 3 months ago
Using Stochastic Causal Trees to Augment Bayesian Networks for Modeling eQTL Datasets
Background: The combination of genotypic and genome-wide expression data arising from segregating populations offers an unprecedented opportunity to model and dissect complex phen...
Kyle C. Chipman, Ambuj K. Singh
FBIT
2007
IEEE
14 years 2 months ago
Unsupervised Learning in Spectral Genome Analysis
The tree representation as a model for organismal evolution has been in use since before Darwin. However, with the recent unprecedented access to biomolecular data it has been dis...
Lutz Hamel, Neha Nahar, Maria S. Poptsova, Olga Zh...
WABI
2009
Springer
128views Bioinformatics» more  WABI 2009»
14 years 3 months ago
Improving Inference of Transcriptional Regulatory Networks Based on Network Evolutionary Models
Abstract. Computational inference of transcriptional regulatory networks remains a challenging problem, in part due to the lack of strong network models. In this paper we present e...
Xiuwei Zhang, Bernard M. E. Moret
JCB
2007
99views more  JCB 2007»
13 years 8 months ago
Duplication and Inversion History of a Tandemly Repeated Genes Family
Given a phylogenetic tree for a family of tandemly repeated genes and their signed order on the chromosome, we aim to find the minimum number of inversions compatible with an evo...
Mathieu Lajoie, Denis Bertrand, Nadia El-Mabrouk, ...