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» Inferring gene regression networks with model trees
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BMCBI
2007
143views more  BMCBI 2007»
13 years 8 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
14 years 8 days ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert
BMCBI
2011
13 years 6 days ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
NIPS
2001
13 years 10 months ago
Infinite Mixtures of Gaussian Process Experts
We present an extension to the Mixture of Experts (ME) model, where the individual experts are Gaussian Process (GP) regression models. Using an input-dependent adaptation of the ...
Carl Edward Rasmussen, Zoubin Ghahramani
CSDA
2006
169views more  CSDA 2006»
13 years 8 months ago
Generalized structured additive regression based on Bayesian P-splines
Generalized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Ba...
Andreas Brezger, Stefan Lang