58933 search results - page 11690 / 11787 » Information |
153
click to vote
BMCBI
2010
14 years 11 months ago
2010
Background: We suggest a new type of modeling approach for the coarse grained, particle-based spatial simulation of combinatorially complex chemical reaction systems. In our appro...
149
click to vote
BMCBI
2010
14 years 11 months ago
2010
Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
163
click to vote
BMCBI
2010
14 years 11 months ago
2010
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
161
click to vote
BMCBI
2010
14 years 11 months ago
2010
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
152
click to vote
BMCBI
2010
14 years 11 months ago
2010
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...