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BMCBI
2008
71views more  BMCBI 2008»
13 years 10 months ago
Examining the significance of fingerprint-based classifiers
Background: Experimental examinations of biofluids to measure concentrations of proteins or their fragments or metabolites are being explored as a means of early disease detection...
Brian T. Luke, Jack R. Collins
BMCBI
2010
177views more  BMCBI 2010»
13 years 10 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
BMCBI
2008
135views more  BMCBI 2008»
13 years 10 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2008
97views more  BMCBI 2008»
13 years 10 months ago
Comparison study on k-word statistical measures for protein: From sequence to 'sequence space'
Background: Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the s...
Qi Dai, Tian-Ming Wang
BMCBI
2007
94views more  BMCBI 2007»
13 years 10 months ago
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...
Philippe Lamy, Claus L. Andersen, Lars Dyrskjot, N...
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