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    BMCBI
    2007
    93views more  BMCBI 2007»
    Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies
    13 years 9 months ago
    Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies
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    Background: Current efforts within the biomedical ontology community focus on achieving interoperability between various biomedical ontologies that cover a range of diverse domain...
    Robert Hoehndorf, Frank Loebe, Janet Kelso, Heinri...
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    BMCBI
    2008
    202views more  BMCBI 2008»
    Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
    13 years 9 months ago
    Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
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    Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
    Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
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    BMCBI
    2007
    139views more  BMCBI 2007»
    Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
    13 years 9 months ago
    Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
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    Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
    Andrew S. Peek
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    BMCBI
    2010
    136views more  BMCBI 2010»
    Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
    13 years 9 months ago
    Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
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    Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
    Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
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    BMCBI
    2007
    126views more  BMCBI 2007»
    High-throughput identification of interacting protein-protein binding sites
    13 years 9 months ago
    High-throughput identification of interacting protein-protein binding sites
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    Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
    Jo-Lan Chung, Wei Wang, Philip E. Bourne
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