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» Information Theoretic Approaches to Whole Genome Phylogenies
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BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Automated simultaneous analysis phylogenetics (ASAP): an enabling tool for phlyogenomics
Background: The availability of sequences from whole genomes to reconstruct the tree of life has the potential to enable the development of phylogenomic hypotheses in ways that ha...
Indra Neil Sarkar, Mary G. Egan, Gloria M. Coruzzi...
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
BIGSdb: Scalable analysis of bacterial genome variation at the population level
Background: The opportunities for bacterial population genomics that are being realised by the application of parallel nucleotide sequencing require novel bioinformatics platforms...
Keith A. Jolley, Martin C. J. Maiden
BMCBI
2007
200views more  BMCBI 2007»
13 years 7 months ago
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
Ágnes Baross, Allen D. Delaney, H. Irene Li...
RECOMB
2005
Springer
14 years 8 months ago
A Framework for Orthology Assignment from Gene Rearrangement Data
Abstract. Gene rearrangements have been used successfully in phylogenetic reconstruction and comparative genomics, but usually under the assumption that all genomes have the same g...
Krister M. Swenson, Nicholas D. Pattengale, Bernar...
BMCBI
2006
107views more  BMCBI 2006»
13 years 7 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...