Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...