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BMCBI
2007
94views more  BMCBI 2007»
13 years 7 months ago
False positive reduction in protein-protein interaction predictions using gene ontology annotations
Background: Many crucial cellular operations such as metabolism, signalling, and regulations are based on protein-protein interactions. However, the lack of robust protein-protein...
Mahmood A. Mahdavi, Yen-Han Lin
BMCBI
2008
86views more  BMCBI 2008»
13 years 7 months ago
Predicting protein linkages in bacteria: Which method is best depends on task
Background: Applications of computational methods for predicting protein functional linkages are increasing. In recent years, several bacteria-specific methods for predicting link...
Anis Karimpour-Fard, Sonia M. Leach, Ryan T. Gill,...
BMCBI
2005
78views more  BMCBI 2005»
13 years 7 months ago
PREP-Mt: predictive RNA editor for plant mitochondrial genes
Background: In plants, RNA editing is a process that converts specific cytidines to uridines and uridines to cytidines in transcripts from virtually all mitochondrial protein-codi...
Jeffrey P. Mower
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...