Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
The availability of an ever increasing amount of data sources due to recent advances in high throughput biotechnologies opens unprecedented opportunities for genome-wide gene funct...
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...