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BMCBI
2007
88views more  BMCBI 2007»
13 years 7 months ago
Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
BMCBI
2006
182views more  BMCBI 2006»
13 years 7 months ago
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
BMCBI
2007
152views more  BMCBI 2007»
13 years 7 months ago
Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
Miguel Arenas, David Posada
BMCBI
2004
150views more  BMCBI 2004»
13 years 7 months ago
SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Chunlin Wang, Elliot J. Lefkowitz