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» Integrated Protein Interaction Networks for 11 Microbes
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RECOMB
2003
Springer
14 years 10 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
BMCBI
2005
127views more  BMCBI 2005»
13 years 9 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
RECOMB
2006
Springer
14 years 10 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
SNPD
2004
13 years 11 months ago
Prediction of Protein Dispensability through Integrated Analysis of Multiple-Source High-Throughput Data
Protein dispensability is fundamental to understanding of gene function and evolution. It is usually studied at the individual gene phenotype level. Recent advances in generating ...
Yu Chen, Dong Xu
CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
14 years 3 months ago
A Topological Measurement for Weighted Protein Interaction Network
High-throughput methods for detecting protein-protein interactions (PPI) have given researchers an initial global picture of protein interactions on a genomic scale. The usefulnes...
Pengjun Pei, Aidong Zhang