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BMCBI
2006
175views more  BMCBI 2006»
13 years 7 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
BMCBI
2010
126views more  BMCBI 2010»
13 years 7 months ago
Simulation of a Petri net-based Model of the Terpenoid Biosynthesis Pathway
Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this ...
Aliah Hazmah Hawari, Zeti-Azura Mohamed-Hussein
BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
CMSB
2006
Springer
13 years 11 months ago
Type Inference in Systems Biology
Type checking and type inference are important concepts and methods of programming languages and software engineering. Type checking is a way to ensure some level of consistency, d...
François Fages, Sylvain Soliman
BMCBI
2010
126views more  BMCBI 2010»
13 years 5 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...