Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding...
Direct manipulation involves a large number of interacting psychological mechanisms that make the performance of a given interface hard to predict on intuitive or informal grounds...
Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach f...
Changhui Yan, Michael Terribilini, Feihong Wu, Rob...