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» Interactive Protein Manipulation
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BMCBI
2010
107views more  BMCBI 2010»
13 years 2 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy
NAR
2011
222views Computer Vision» more  NAR 2011»
12 years 10 months ago
Effective - a database of predicted secreted bacterial proteins
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding...
Marc-André Jehl, Roland Arnold, Thomas Ratt...
CHI
2001
ACM
13 years 11 months ago
Towards demystification of direct manipulation: cognitive modeling charts the gulf of execution
Direct manipulation involves a large number of interacting psychological mechanisms that make the performance of a given interface hard to predict on intuitive or informal grounds...
David E. Kieras, David Meyer, James A. Ballas
BMCBI
2006
95views more  BMCBI 2006»
13 years 7 months ago
Predicting DNA-binding sites of proteins from amino acid sequence
Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach f...
Changhui Yan, Michael Terribilini, Feihong Wu, Rob...