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BMCBI
2008
131views more  BMCBI 2008»
13 years 7 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
Discovering functional interaction patterns in protein-protein interaction networks
Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of ge...
Mehmet E. Turanalp, Tolga Can
BMCBI
2005
95views more  BMCBI 2005»
13 years 7 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
BMCBI
2006
150views more  BMCBI 2006»
13 years 7 months ago
Protein structure similarity from principle component correlation analysis
Background: Owing to rapid expansion of protein structure databases in recent years, methods of structure comparison are becoming increasingly effective and important in revealing...
Xiaobo Zhou, James Chou, Stephen T. C. Wong
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...