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CANDC
2006
ACM
13 years 9 months ago
Unraveling the nature of the segmentation clock: Intrinsic disorder of clock proteins and their interaction map
Vertebrate segmentation has been proved to be under a strict temporal control governed by a biological clock, known as the segmentation clock. The present experimental evidence su...
Sourav Roy, Santiago Schnell, Predrag Radivojac
BMCBI
2004
112views more  BMCBI 2004»
13 years 8 months ago
Predicting co-complexed protein pairs using genomic and proteomic data integration
Background: Identifying all protein-protein interactions in an organism is a major objective of proteomics. A related goal is to know which protein pairs are present in the same p...
Lan V. Zhang, Sharyl L. Wong, Oliver D. King, Fred...
LION
2009
Springer
135views Optimization» more  LION 2009»
14 years 3 months ago
Neural Network Pairwise Interaction Fields for Protein Model Quality Assessment
We present a new knowledge-based Model Quality Assessment Program (MQAP) at the residue level which evaluates single protein structure models. We use a tree representation of the ...
Alberto J. M. Martin, Alessandro Vullo, Gianluca P...
BMCBI
2007
102views more  BMCBI 2007»
13 years 9 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
BMCBI
2004
150views more  BMCBI 2004»
13 years 8 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty