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BMCBI
2010
113views more  BMCBI 2010»
13 years 10 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
BMCBI
2007
162views more  BMCBI 2007»
13 years 10 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2007
112views more  BMCBI 2007»
13 years 10 months ago
Integrated olfactory receptor and microarray gene expression databases
Background: Gene expression patterns of olfactory receptors (ORs) are an important component of the signal encoding mechanism in the olfactory system since they determine the inte...
Nian Liu, Chiquito J. Crasto, Minghong Ma
BMCBI
2007
124views more  BMCBI 2007»
13 years 10 months ago
BioInfer: a corpus for information extraction in the biomedical domain
Background: Lately, there has been a great interest in the application of information extraction methods to the biomedical domain, in particular, to the extraction of relationship...
Sampo Pyysalo, Filip Ginter, Juho Heimonen, Jari B...
BMCBI
2008
130views more  BMCBI 2008»
13 years 10 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...