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BMCBI
2010
13 years 10 months ago
2010
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
BMCBI
2010
13 years 10 months ago
2010
Background: Many biological functions involve various protein-protein interactions (PPIs). Elucidating such interactions is crucial for understanding general principles of cellula...
BMCBI
2007
13 years 10 months ago
2007
Background: The existence of negative correlations between degrees of interacting proteins is being discussed since such negative degree correlations were found for the large-scal...
BMCBI
2007
13 years 10 months ago
2007
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
BMCBI
2007
13 years 10 months ago
2007
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...