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BMCBI
2006
166views more  BMCBI 2006»
13 years 10 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2006
141views more  BMCBI 2006»
13 years 10 months ago
Visual setup of logical models of signaling and regulatory networks with ProMoT
Background: The analysis of biochemical networks using a logical (Boolean) description is an important approach in Systems Biology. Recently, new methods have been proposed to ana...
Julio Saez-Rodriguez, Sebastian Mirschel, Rebecca ...
BMCBI
2006
129views more  BMCBI 2006»
13 years 10 months ago
A literature-based similarity metric for biological processes
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
BMCBI
2006
122views more  BMCBI 2006»
13 years 10 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2007
209views more  BMCBI 2007»
13 years 10 months ago
SYMBIOmatics: Synergies in Medical Informatics and Bioinformatics - exploring current scientific literature for emerging topics
Background: The SYMBIOmatics Specific Support Action (SSA) is "an information gathering and dissemination activity" that seeks "to identify synergies between the bi...
Dietrich Rebholz-Schuhmann, Graham Cameron, Domini...