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BMCBI
2010
83views more  BMCBI 2010»
13 years 10 months ago
An effective approach for generating a three-Cys2His2 zinc-finger-DNA complex model by docking
Background: Determination of protein-DNA complex structures with both NMR and X-ray crystallography remains challenging in many cases. High Ambiguity-Driven DOCKing (HADDOCK) is a...
Chun-Chi Chou, M. Rajasekaran, Chinpan Chen
BMCBI
2008
129views more  BMCBI 2008»
13 years 10 months ago
EMAAS: An extensible grid-based Rich Internet Application for microarray data analysis and management
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...
Geraint Barton, J. C. Abbott, Norie Chiba, D. W. H...
BMCBI
2007
159views more  BMCBI 2007»
13 years 10 months ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...
IANDC
2008
141views more  IANDC 2008»
13 years 9 months ago
Graph connectivity, partial words, and a theorem of Fine and Wilf
The problem of computing periods in words, or finite sequences of symbols from a finite alphabet, has important applications in several areas including data compression, string se...
Francine Blanchet-Sadri, Deepak Bal, Gautam Sisodi...
BMCBI
2007
144views more  BMCBI 2007»
13 years 9 months ago
InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic ge
Background: Although many genomic features have been used in the prediction of proteinprotein interactions (PPIs), frequently only one is used in a computational method. After rea...
Jingchun Sun, Yan Sun, Guohui Ding, Qi Liu, Chuan ...
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