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» InteroPORC: an automated tool to predict highly conserved pr...
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BMCBI
2006
182views more  BMCBI 2006»
13 years 6 months ago
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
JCB
2007
83views more  JCB 2007»
13 years 6 months ago
Evolutionary Networks in the Formatted Protein Sequence Space
In our recent work, a new approach to establish sequence relatedness, by walking through the protein sequence space, was introduced. The sequence space is built from 20 amino acid...
Zakharia M. Frenkel, Edward N. Trifonov
BMCBI
2007
114views more  BMCBI 2007»
13 years 6 months ago
Probabilistic prediction and ranking of human protein-protein interactions
Background: Although the prediction of protein-protein interactions has been extensively investigated for yeast, few such datasets exist for the far larger proteome in human. Furt...
Michelle S. Scott, Geoffrey J. Barton
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
INTEGRATOR: interactive graphical search of large protein interactomes over the Web
Background: The rapid growth of protein interactome data has elevated the necessity and importance of network analysis tools. However, unlike pure text data, network search spaces...
Aaron N. Chang, Jason McDermott, Zachary Frazier, ...
BMCBI
2006
94views more  BMCBI 2006»
13 years 6 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...