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» Interpreting distributed ontologies
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BMCBI
2008
114views more  BMCBI 2008»
13 years 9 months ago
Partial mixture model for tight clustering of gene expression time-course
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
Yinyin Yuan, Chang-Tsun Li, Roland Wilson
BMCBI
2008
122views more  BMCBI 2008»
13 years 9 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
BMCBI
2007
99views more  BMCBI 2007»
13 years 9 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi
BMCBI
2005
114views more  BMCBI 2005»
13 years 9 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
LOGCOM
2007
130views more  LOGCOM 2007»
13 years 9 months ago
A Logic for Concepts and Similarity
Categorisation of objects into classes is currently supported by (at least) two ‘orthogonal’ methods. In logic-based approaches, classifications are defined through ontologi...
Mikhail Sheremet, Dmitry Tishkovsky, Frank Wolter,...