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» Intrusion Detection: A Bioinformatics Approach
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BMCBI
2007
129views more  BMCBI 2007»
15 years 4 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
BMCBI
2010
136views more  BMCBI 2010»
15 years 4 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
130
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WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
15 years 10 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
ISBRA
2007
Springer
15 years 10 months ago
A Bootstrap Correspondence Analysis for Factorial Microarray Experiments with Replications
Characterized by simultaneous measurement of the effects of experimental factors and their interactions, the economic and efficient factorial design is well accepted in microarray ...
Qihua Tan, Jesper Dahlgaard, Basem M. Abdallah, We...
COMPLIFE
2006
Springer
15 years 7 months ago
Beating the Noise: New Statistical Methods for Detecting Signals in MALDI-TOF Spectra Below Noise Level
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...