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BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2007
109views more  BMCBI 2007»
15 years 6 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
BMCBI
2008
116views more  BMCBI 2008»
15 years 6 months ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
BMCBI
2006
85views more  BMCBI 2006»
15 years 6 months ago
On single and multiple models of protein families for the detection of remote sequence relationships
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
James A. Casbon, Mansoor A. S. Saqi
CGF
2006
183views more  CGF 2006»
15 years 6 months ago
Data-driven Local Coordinate Systems for Image-Based Rendering
Image-based representations of an object profit from known geometry. The more accurate this geometry is known, the better corresponding pixels in the different images can be align...
Gero Müller, Ralf Sarlette, Reinhard Klein