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» Is the protein folding an aim-oriented process
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BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
High throughput profile-profile based fold recognition for the entire human proteome
Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
BMCBI
2008
74views more  BMCBI 2008»
13 years 8 months ago
Prediction of mucin-type O-glycosylation sites in mammalian proteins using the composition of k-spaced amino acid pairs
Background: As one of the most common protein post-translational modifications, glycosylation is involved in a variety of important biological processes. Computational identificat...
Yong-Zi Chen, Yu-Rong Tang, Zhi-Ya Sheng, Ziding Z...
BMCBI
2007
233views more  BMCBI 2007»
13 years 8 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
BMCBI
2004
151views more  BMCBI 2004»
13 years 7 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
LBM
2007
13 years 9 months ago
Syntactic Features for Protein-Protein Interaction Extraction
Background: Extracting Protein-Protein Interactions (PPI) from research papers is a way of translating information from English to the language used by the databases that store th...
Rune Sætre, Kenji Sagae, Jun-ichi Tsujii