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BMCBI
2010
13 years 10 months ago
2010
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
BMCBI
2010
13 years 10 months ago
2010
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
BMCBI
2010
13 years 10 months ago
2010
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
BMCBI
2010
13 years 10 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
BMCBI
2010
13 years 10 months ago
2010
Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subc...