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BMCBI
2005
93views more  BMCBI 2005»
13 years 7 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2004
208views more  BMCBI 2004»
13 years 7 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
CORR
2002
Springer
131views Education» more  CORR 2002»
13 years 7 months ago
Ownership Confinement Ensures Representation Independence for Object-Oriented Programs
for data abstraction and justifies reasoning by simulation. Representation independence has been shown for a variety of languages and constructs but not for shared references to mu...
Anindya Banerjee, David A. Naumann
JAIR
2000
123views more  JAIR 2000»
13 years 7 months ago
Backbone Fragility and the Local Search Cost Peak
The local search algorithm WSat is one of the most successful algorithms for solving the satisfiability (SAT) problem. It is notably effective at solving hard Random 3-SAT instanc...
Josh Singer, Ian P. Gent, Alan Smaill
NRHM
2000
149views more  NRHM 2000»
13 years 7 months ago
Navigable history: a reader's view of writer's time
Collecting, analyzing, and sharing information via a hypertext results in the continuous modification of information content over a long period of time. Such tasks will benefit fr...
Frank M. Shipman III, Hao-wei Hsieh