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» Large Scale Matching for Position Weight Matrices
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IUI
2009
ACM
14 years 5 months ago
Searching large indexes on tiny devices: optimizing binary search with character pinning
The small physical size of mobile devices imposes dramatic restrictions on the user interface (UI). With the ever increasing capacity of these devices as well as access to large o...
Guy Shani, Christopher Meek, Tim Paek, Bo Thiesson...
BMCBI
2010
121views more  BMCBI 2010»
13 years 8 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
SIAMJO
2010
155views more  SIAMJO 2010»
13 years 3 months ago
Optimal Portfolio Execution Strategies and Sensitivity to Price Impact Parameters
When liquidating a portfolio of large blocks of risky assets, an institutional investor wants to minimize the cost as well as the risk of execution. An optimal execution strategy ...
Somayeh Moazeni, Thomas F. Coleman, Yuying Li
ICASSP
2011
IEEE
13 years 4 days ago
Nonnegative 3-way tensor factorization via conjugate gradient with globally optimal stepsize
This paper deals with the minimal polyadic decomposition (also known as canonical decomposition or Parafac) of a 3way array, assuming each entry is positive. In this case, the low...
Jean-Philip Royer, Pierre Comon, Nadège Thi...
BMCBI
2010
167views more  BMCBI 2010»
13 years 8 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...