Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
Background: Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological dat...
Xiong Liu, Xueping Yu, Donald J. Zack, Heng Zhu, J...
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
Expressed sequence tags, abbreviated ESTs, are DNA fragments experimentally derived from expressed portions of genes. Clustering of ESTs is essential for gene recognition and unde...
Background: The definition of a distance measure plays a key role in the evaluation of different clustering solutions of gene expression profiles. In this empirical study we compa...