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    BMCBI
    2010
    132views more  BMCBI 2010»
    Data structures and compression algorithms for high-throughput sequencing technologies
    13 years 8 months ago
    Data structures and compression algorithms for high-throughput sequencing technologies
    Download  www.biomedcentral.com
    Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
    Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
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    BMCBI
    2007
    147views more  BMCBI 2007»
    Improved residue contact prediction using support vector machines and a large feature set
    13 years 8 months ago
    Improved residue contact prediction using support vector machines and a large feature set
    Download  www.eecs.ucf.edu
    Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
    Jianlin Cheng, Pierre Baldi
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    BMCBI
    2007
    166views more  BMCBI 2007»
    Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
    13 years 8 months ago
    Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
    Download  www.biomedcentral.com
    Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
    Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
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    BMCBI
    2007
    233views more  BMCBI 2007»
    160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
    13 years 8 months ago
    160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
    Download  www.biomedcentral.com
    Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
    Isaac T. S. Li, Warren Shum, Kevin Truong
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    BMCBI
    2008
    160views more  BMCBI 2008»
    VariVis: a visualisation toolkit for variation databases
    13 years 8 months ago
    VariVis: a visualisation toolkit for variation databases
    Download  www.nugo.org
    Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
    Timothy D. Smith, Richard G. H. Cotton
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