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» Learning Functions from Imperfect Positive Data
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BMCBI
2007
141views more  BMCBI 2007»
13 years 8 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
BMCBI
2006
103views more  BMCBI 2006»
13 years 9 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
ICANN
2007
Springer
14 years 22 days ago
Neural Network Approach for Mass Spectrometry Prediction by Peptide Prototyping
In todays bioinformatics, Mass spectrometry (MS) is the key technique for the identification of proteins. A prediction of spectrum peak intensities from pre computed molecular feat...
Alexandra Scherbart, Wiebke Timm, Sebastian Bö...
EMNLP
2011
12 years 8 months ago
Relation Extraction with Relation Topics
This paper describes a novel approach to the semantic relation detection problem. Instead of relying only on the training instances for a new relation, we leverage the knowledge l...
Chang Wang, James Fan, Aditya Kalyanpur, David Gon...
BMCBI
2008
92views more  BMCBI 2008»
13 years 9 months ago
A semiparametric modeling framework for potential biomarker discovery and the development of metabonomic profiles
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
Samiran Ghosh, David F. Grant, Dipak K. Dey, Denni...