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» Learning Instance-Specific Predictive Models
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BMCBI
2008
155views more  BMCBI 2008»
13 years 9 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2007
136views more  BMCBI 2007»
13 years 9 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
AAAI
2007
13 years 11 months ago
Predictive Exploration for Autonomous Science
Often remote investigations use autonomous agents to observe an environment on behalf of absent scientists. Predictive exploration improves these systems’ efficiency with onboa...
David R. Thompson
BMCBI
2006
216views more  BMCBI 2006»
13 years 9 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
BMCBI
2007
116views more  BMCBI 2007»
13 years 9 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...