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BMCBI
2005
103views more  BMCBI 2005»
13 years 6 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2007
93views more  BMCBI 2007»
13 years 6 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
BIBE
2001
IEEE
13 years 10 months ago
Gene Classification using Expression Profiles: A Feasibility Study
As various genome sequencing projects have already been completed or are near completion, genome researchers are shifting their focus from structural genomics to functional genomi...
Michihiro Kuramochi, George Karypis
BMCBI
2007
186views more  BMCBI 2007»
13 years 6 months ago
GeneBins: a database for classifying gene expression data, with application to plant genome arrays
Background: To interpret microarray experiments, several ontological analysis tools have been developed. However, current tools are limited to specific organisms. Results: We deve...
Nicolas Goffard, Georg Weiller
ICML
2001
IEEE
14 years 7 months ago
Feature selection for high-dimensional genomic microarray data
We report on the successful application of feature selection methods to a classification problem in molecular biology involving only 72 data points in a 7130 dimensional space. Ou...
Eric P. Xing, Michael I. Jordan, Richard M. Karp