388 search results - page 5 / 78 » Learning Methods for DNA Binding in Computational Biology |
TCBB
2008
13 years 7 months ago
2008
The problem of discovering novel motifs of binding sites is important to the understanding of gene regulatory networks. Motifs are generally represented by matrices (PWM or PSSM) o...
BMCBI
2006
13 years 7 months ago
2006
Background: Tangle analysis has been applied successfully to study proteins which bind two segments of DNA and can knot and link circular DNA. We show how tangle analysis can be e...
BMCBI
2007
13 years 7 months ago
2007
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
BMCBI
2004
13 years 7 months ago
2004
Background: Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which th...
BMCBI
2007
13 years 7 months ago
2007
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...