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BMCBI
2010
13 years 7 months ago
2010
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
BMCBI
2010
13 years 7 months ago
2010
Background: The construction of interaction networks between proteins is central to understanding the underlying biological processes. However, since many useful relations are exc...
BMCBI
2010
13 years 7 months ago
2010
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
BMCBI
2010
13 years 7 months ago
2010
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
BMCBI
2007
13 years 7 months ago
2007
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...