Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Background: Increasing amount of data from comparative genomics, and newly developed technologies producing accurate gene expression data facilitate the study of the expression di...
Xianjun Dong, Altuna Akalin, Yogita Sharma, Boris ...
Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Background: Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological dat...
Xiong Liu, Xueping Yu, Donald J. Zack, Heng Zhu, J...