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BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
SODA
2012
ACM
212views Algorithms» more  SODA 2012»
11 years 10 months ago
Parallelism and time in hierarchical self-assembly
We study the role that parallelism plays in time complexariants of Winfree’s abstract Tile Assembly Model (aTAM), a model of molecular algorithmic self-assembly. In the “hiera...
Ho-Lin Chen, David Doty
BMCBI
2007
165views more  BMCBI 2007»
13 years 7 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
STOC
2012
ACM
209views Algorithms» more  STOC 2012»
11 years 10 months ago
Nearly optimal solutions for the chow parameters problem and low-weight approximation of halfspaces
The Chow parameters of a Boolean function f : {−1, 1}n → {−1, 1} are its n + 1 degree-0 and degree-1 Fourier coefficients. It has been known since 1961 [Cho61, Tan61] that ...
Anindya De, Ilias Diakonikolas, Vitaly Feldman, Ro...
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