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    BMCBI
    2007
    130views more  BMCBI 2007»
    A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
    13 years 9 months ago
    A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
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    Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
    Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
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    BMCBI
    2008
    115views more  BMCBI 2008»
    Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
    13 years 9 months ago
    Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
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    Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson corre...
    Jianchao Yao, Chunqi Chang, Mari L. Salmi, Yeung S...
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    BMCBI
    2010
    146views more  BMCBI 2010»
    Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
    13 years 9 months ago
    Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
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    Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
    Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
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    BMCBI
    2008
    186views more  BMCBI 2008»
    Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
    13 years 9 months ago
    Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
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    Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
    Min Zhang, Dabao Zhang, Martin T. Wells
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    BMCBI
    2007
    81views more  BMCBI 2007»
    PADB : Published Association Database
    13 years 9 months ago
    PADB : Published Association Database
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    Background: Although molecular pathway information and the International HapMap Project data can help biomedical researchers to investigate the aetiology of complex diseases more ...
    Hwanseok Rhee, Jin-Sung Lee
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