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BMCBI
2010
110views more  BMCBI 2010»
13 years 8 months ago
Discovering local patterns of co - evolution: computational aspects and biological examples
Background: Co-evolution is the process in which two (or more) sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn abo...
Tamir Tuller, Yifat Felder, Martin Kupiec
NECO
2011
13 years 2 months ago
Least Squares Estimation Without Priors or Supervision
Selection of an optimal estimator typically relies on either supervised training samples (pairs of measurements and their associated true values), or a prior probability model for...
Martin Raphan, Eero P. Simoncelli
BMCBI
2010
165views more  BMCBI 2010»
13 years 8 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
HIPEAC
2009
Springer
14 years 2 months ago
Collective Optimization
Abstract. Iterative compilation is an efficient approach to optimize programs on rapidly evolving hardware, but it is still only scarcely used in practice due to a necessity to gat...
Grigori Fursin, Olivier Temam