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BMCBI
2010
183views more  BMCBI 2010»
13 years 9 months ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...
BMCBI
2010
109views more  BMCBI 2010»
13 years 9 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
113views more  BMCBI 2008»
13 years 9 months ago
SNPFile - A software library and file format for large scale association mapping and population genetics studies
Background: High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies. ...
Jesper Nielsen, Thomas Mailund
BMCBI
2007
88views more  BMCBI 2007»
13 years 9 months ago
Computational analysis of the relationship between allergenicity and digestibility of allergenic proteins in simulated gastric f
Background: Safety assessment of genetically modified (GM) food, with regard to allergenic potential of transgene-encoded xenoproteins, typically involves several different method...
Bingjun Jiang, Hong Qu, Yuanlei Hu, Ting Ni, Zhong...
BMCBI
2007
94views more  BMCBI 2007»
13 years 9 months ago
Lightweight genome viewer: portable software for browsing genomics data in its chromosomal context
Background: Lightweight genome viewer (lwgv) is a web-based tool for visualization of sequence annotations in their chromosomal context. It performs most of the functions of large...
Jeremiah J. Faith, Andrew J. Olson, Timothy S. Gar...
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