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BMCBI
2008
145views more  BMCBI 2008»
13 years 9 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2008
123views more  BMCBI 2008»
13 years 9 months ago
Functional module detection by functional flow pattern mining in protein interaction networks
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Young-Rae Cho, Lei Shi, Aidong Zhang
BMCBI
2008
144views more  BMCBI 2008»
13 years 9 months ago
Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
Background: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such as alignments comprising te...
Olivo Miotto, Tin Wee Tan, Vladimir Brusic
CORR
2008
Springer
116views Education» more  CORR 2008»
13 years 9 months ago
An Evidential Path Logic for Multi-Relational Networks
Multi-relational networks are used extensively to structure knowledge. Perhaps the most popular instance, due to the widespread adoption of the Semantic Web, is the Resource Descr...
Marko A. Rodriguez, Joe Geldart
BMCBI
2006
128views more  BMCBI 2006»
13 years 9 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...